ACTR1A antibody (Middle Region)
-
- Target See all ACTR1A Antibodies
- ACTR1A (Alpha Centractin (ACTR1A))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ACTR1A antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- AIKERACYLS INPQKDETLE TEKAQYYLPD GSTIEIGPSR FRAPELLFRP
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ACTR1A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ACTR1A
- Top Product
- Discover our top product ACTR1A Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 376 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- ACTR1A (Alpha Centractin (ACTR1A))
- Alternative Name
- ACTR1A (ACTR1A Products)
- Synonyms
- ARP1 antibody, CTRN1 antibody, Arp1 antibody, alpha-Arp1 antibody, arp1 antibody, centractin antibody, ctrn1 antibody, ACTR1A antibody, ARP1 actin related protein 1 homolog A antibody, ARP1 actin-related protein 1A, centractin alpha antibody, ARP1 actin-related protein 1 homolog A, centractin alpha antibody, ARP1 actin related protein 1 homolog A L homeolog antibody, alpha-centractin antibody, actin-2 antibody, ACTR1A antibody, Actr1a antibody, actr1a.L antibody, actr1a antibody, PTRG_02540 antibody, PAAG_06972 antibody, MCYG_01044 antibody, VDBG_00685 antibody, MGYG_00946 antibody, DICPUDRAFT_88548 antibody, PGTG_04034 antibody, Tsp_06409 antibody
- Background
-
ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARP1, CTRN1
Protein Interaction Partner: HUWE1, SUMO2, UBC, NUP133, DCTN4, MYCBP, DCTN3, DCTN2, ACTR1B, LMNB1, COG3, ACTR10, SMURF1, RRS1, PSMD1, PSMC4, MYH9, MCM7, COPS5, CUL1, CUL3, SUMO1, Cep76, Actr1a, Dctn1, Capza1, HDAC6, SPTBN2, SPTBN1, NUMA1, BICD2,
Protein Size: 376 - Molecular Weight
- 41 kDa
- Gene ID
- 10121
- NCBI Accession
- NM_005736, NP_005727
- UniProt
- P61163
- Pathways
- M Phase
-