HSC70 Interacting Protein HIP antibody (N-Term)

Catalog No. ABIN2787786

Product Details anti-HSC70 Interacting Protein HIP Antibody

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSC70 Interacting Protein HIP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVPPATHKAK SEENTKEEKR DKTTEENIKT EELSSEESDL EIDNEGVIEP

Predicted Reactivity: Cow: 77%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against St13. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse St13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 371 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSC70 Interacting Protein HIP

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Alternative Name: St13 (ST13 Products)

Synonyms: CG32789 antibody, Dmel\\CG32789 antibody, anon-EST:fe1A9 antibody, 1110007I03Rik antibody, 3110002K08Rik antibody, AW555194 antibody, HIP antibody, HOP antibody, HSPABP antibody, HSPABP1 antibody, PRO0786 antibody, SNC6 antibody, p48 antibody, AAG2 antibody, FAM10A1 antibody, FAM10A4 antibody, P48 antibody, Hsc/Hsp70-interacting protein antibody, suppression of tumorigenicity 13 antibody, ST13, Hsp70 interacting protein antibody, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) antibody, HIP antibody, St13 antibody, ST13 antibody

Background: One HIP oligomer binds the ATPase domains of at least two HSC70 Molecules dependent on activation of the HSC70 ATPase by HSP40. St13 stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
Alias Symbols: 1110007I03Rik, 3110002K08Rik, AW555194, HIP, HOP, HSPABP, HSPABP1, PRO0786, SNC6, p48
Protein Size: 371

Molecular Weight: 42 kDa

Gene ID: 70356

NCBI Accession: NM_133726, NP_598487

UniProt: Q99L47