Selectin E/CD62e antibody (N-Term)
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- Target See all Selectin E/CD62e (SELE) Antibodies
- Selectin E/CD62e (SELE) (Selectin E (SELE))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Sheep, Cow, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Selectin E/CD62e antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK DVGMWNDERC
- Predicted Reactivity
- Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%
- Characteristics
- This is a rabbit polyclonal antibody against SELE. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SELE
- Top Product
- Discover our top product SELE Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 610 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- Alternative Name
- SELE (SELE Products)
- Synonyms
- SELE antibody, CD62E antibody, ELAM antibody, ELAM1 antibody, ESEL antibody, LECAM2 antibody, E-selectin antibody, Elam antibody, selectin E antibody, selectin, endothelial cell antibody, SELE antibody, Sele antibody
- Background
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The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Alias Symbols: CD62E, ELAM, ELAM1, ESEL, LECAM2
Protein Interaction Partner: LGALS3BP, SELL, SERPING1, PXN, PTK2, GLG1, SELPLG, FLNA, VCL, PTPN11, PLCG1, CD44, ACTN2, TLN1,
Protein Size: 610 - Molecular Weight
- 64 kDa
- Gene ID
- 6401
- NCBI Accession
- NM_000450, NP_000441
- UniProt
- P16581
- Pathways
- Thromboxane A2 Receptor Signaling
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