ZRANB1 antibody (C-Term)

Catalog No. ABIN2788030

Product Details anti-ZRANB1 Antibody

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Rat, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZRANB1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GAGANLNTDD DVTITFLPLV DSERKLLHVH FLSAQELGNE EQQEKLLREW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ZRANB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZRANB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 708 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZRANB1

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Alternative Name: ZRANB1 (ZRANB1 Products)

Synonyms: TRABID antibody, 9330160G10Rik antibody, D7Wsu87e antibody, Gm1956 antibody, Trabid antibody, trabid antibody, zranb1 antibody, zgc:154177 antibody, zinc finger RANBP2-type containing 1 antibody, zinc finger, RAN-binding domain containing 1 antibody, zinc finger RANBP2-type containing 1 L homeolog antibody, zinc finger, RAN-binding domain containing 1b antibody, ZRANB1 antibody, Zranb1 antibody, zranb1.L antibody, zranb1b antibody, zranb1 antibody

Background: ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains.ZRANB1 acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. ZRANB1 may also modulate TNF-alpha signaling.
Alias Symbols: DKFZp762P2216, TRABID
Protein Interaction Partner: Btrc, UBC, CORO7, STRIP1, CTTNBP2, CTTNBP2NL, STRN3, STRN4, HECTD1, SLMAP, STRN, UBE2S, TRAF6, Apc, PGAM5, STRIP2, CACYBP, FGFR1OP2, MOB4, BICD2, FBXW11, KEAP1, GCC2, MAP4K4, HERC2, ALDH18A1, PPP2R1B,
Protein Size: 708

Molecular Weight: 81 kDa

Gene ID: 54764

NCBI Accession: NM_017580, NP_060050

UniProt: Q9UGI0