ZRANB1 antibody (C-Term)
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- Target See all ZRANB1 Antibodies
- ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Cow, Dog, Horse, Rabbit, Rat, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZRANB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GAGANLNTDD DVTITFLPLV DSERKLLHVH FLSAQELGNE EQQEKLLREW
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against ZRANB1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human ZRANB1
- Top Product
- Discover our top product ZRANB1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 708 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))
- Alternative Name
- ZRANB1 (ZRANB1 Products)
- Synonyms
- TRABID antibody, 9330160G10Rik antibody, D7Wsu87e antibody, Gm1956 antibody, Trabid antibody, trabid antibody, zranb1 antibody, zgc:154177 antibody, zinc finger RANBP2-type containing 1 antibody, zinc finger, RAN-binding domain containing 1 antibody, zinc finger RANBP2-type containing 1 L homeolog antibody, zinc finger, RAN-binding domain containing 1b antibody, ZRANB1 antibody, Zranb1 antibody, zranb1.L antibody, zranb1b antibody, zranb1 antibody
- Background
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ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains.ZRANB1 acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. ZRANB1 may also modulate TNF-alpha signaling.
Alias Symbols: DKFZp762P2216, TRABID
Protein Interaction Partner: Btrc, UBC, CORO7, STRIP1, CTTNBP2, CTTNBP2NL, STRN3, STRN4, HECTD1, SLMAP, STRN, UBE2S, TRAF6, Apc, PGAM5, STRIP2, CACYBP, FGFR1OP2, MOB4, BICD2, FBXW11, KEAP1, GCC2, MAP4K4, HERC2, ALDH18A1, PPP2R1B,
Protein Size: 708 - Molecular Weight
- 81 kDa
- Gene ID
- 54764
- NCBI Accession
- NM_017580, NP_060050
- UniProt
- Q9UGI0
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