UFD1L antibody (Middle Region)
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- Target See all UFD1L Antibodies
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UFD1L antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NYNEKIYELR VMETKPDKAV SIIECDMNVD FDAPLGYKEP ERQVQHEEST
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against UFD1L. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human UFD1L
- Top Product
- Discover our top product UFD1L Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 307 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
- Alternative Name
- UFD1L (UFD1L Products)
- Synonyms
- UFD1 antibody, Ufd1 antibody, ufd1 antibody, wu:fc55f04 antibody, zgc:92341 antibody, Ufd1l antibody, ubiquitin recognition factor in ER associated degradation 1 antibody, ubiquitin recognition factor in ER-associated degradation 1 antibody, ubiquitin fusion degradation 1 like (yeast) antibody, ubiquitin recognition factor in ER associated degradation 1 S homeolog antibody, ubiquitin fusion degradation protein 1 homolog antibody, Ubiquitin Fusion Degradation (yeast UFD homolog) antibody, UFD1 antibody, Ufd1 antibody, UFD1L antibody, ufd1.S antibody, ufd1l antibody, ufd1 antibody, EHI_125920 antibody, LOC100166745 antibody, LOC100635687 antibody, LOC100648660 antibody, ufd-1 antibody
- Background
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The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Alias Symbols: UFD1
Protein Interaction Partner: HUWE1, YOD1, VCP, UBC, SHFM1, SUZ12, BTRC, EZH2, PDCD4, NPLOC4, NFKBIA, NUB1, NEDD8, CAV1, ADRB2, FAF1, TXLNA, UNC45A, VPS33B, UBE3A, UBE2N, PSMD7, SPRTN, UBXN6, GZMK, ERLIN2, ITPR1, PPHLN1, ANAPC2, TIAM2, TAF1C, TP53, SNX1, MASP1, PIK3CA, NGFR, IGHM, F13
Protein Size: 307 - Molecular Weight
- 34 kDa
- Gene ID
- 7353
- NCBI Accession
- NM_005659, NP_005650
- UniProt
- Q92890
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