SYT12 antibody (N-Term)

Catalog No. ABIN2788090

Product Details anti-SYT12 Antibody

Target: SYT12 (Synaptotagmin XII (SYT12))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AEAREKRVPA WNAQRASTRG PPSRKGSLSI EDTFESISEL GPLELMGREL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SYT12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SYT12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 421 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYT12

Target: SYT12 (Synaptotagmin XII (SYT12))

Alternative Name: SYT12 (SYT12 Products)

Synonyms: zgc:194750 antibody, zgc:194771 antibody, DKFZp459J0427 antibody, SYT11 antibody, sytXII antibody, Srg1 antibody, synaptotagmin 12 antibody, synaptotagmin XII antibody, SYT12 antibody, syt12 antibody, Syt12 antibody

Background: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
Alias Symbols: SRG1, SYT11, sytXII
Protein Interaction Partner: UBC,
Protein Size: 421

Molecular Weight: 46 kDa

Gene ID: 91683

NCBI Accession: NM_177963, NP_808878

UniProt: Q8IV01