DNAJC2 antibody (C-Term)
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- Target See all DNAJC2 Antibodies
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Dog, Cow, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DNAJC2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EINEQIRKEK EEAEARMRQA SKNTEKSTGG GGNGSKNWSE DDLQLLIKAV
- Predicted Reactivity
- Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against DNAJC2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human DNAJC2
- Top Product
- Discover our top product DNAJC2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 621 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
- Alternative Name
- DNAJC2 (DNAJC2 Products)
- Synonyms
- zrf1 antibody, ZRF1 antibody, MPHOSPH11 antibody, MPP11 antibody, ZUO1 antibody, AU020218 antibody, MIDA1 antibody, Zrf1 antibody, Zrf2 antibody, zgc:85671 antibody, DnaJ heat shock protein family (Hsp40) member C2 antibody, DnaJ (Hsp40) homolog, subfamily C, member 2 antibody, dnajc2 antibody, DNAJC2 antibody, Dnajc2 antibody
- Background
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This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
Alias Symbols: MPHOSPH11, MPP11, ZRF1, ZUO1
Protein Interaction Partner: HIST2H2AA3, UBC, RNF2, HSPA14, HSPA8,
Protein Size: 621 - Molecular Weight
- 72 kDa
- Gene ID
- 27000
- NCBI Accession
- NM_014377, NP_055192
- UniProt
- Q99543
- Pathways
- Chromatin Binding
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