CAPNL1 antibody (N-Term)

Catalog No. ABIN2788626

Product Details anti-CAPNL1 Antibody

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Zebrafish (Danio rerio), Goat, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPNL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EFWSALLEKA YAKVNGSYEA LSGGSTSEGF EDFTGGVTEW YELRKAPSDL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CAPN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAPN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 714 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAPNL1

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Alternative Name: CAPN1 (CAPNL1 Products)

Synonyms: CANP antibody, CANP1 antibody, CANPL1 antibody, muCANP antibody, muCL antibody, Capa-1 antibody, Capa1 antibody, mu-calpin antibody, si:ch211-203k12.4 antibody, si:dkeyp-101g1.3 antibody, calpain antibody, calpain 1 antibody, calpain 1, (mu/I) large subunit antibody, calpain 1, (mu/I) large subunit b antibody, calpain 11 antibody, CAPN1 antibody, Capn1 antibody, capn1 antibody, capn1b antibody, CAPN11 antibody

Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: CANP, CANP1, CANPL1, muCANP, muCL
Protein Interaction Partner: UBC, TP53, SUMO2, GINS2, BZW2, YWHAQ, SLC9A3R1, RPS6KA1, RAP1GDS1, PFAS, PEPD, MVD, EIF6, HSPA9, GNS, GLS, GLA, GBP2, EIF4E, EEF2, ECHS1, CASP7, ASS1, LDHAL6B, GINS3, SMEK2, BCCIP, CNDP2, G6PD, HNRNPD, BAG3, SPTAN1, TINAGL1, PRMT5, CREG1, VIM, SLIT3, SH3B
Protein Size: 714

Molecular Weight: 82 kDa

Gene ID: 823

NCBI Accession: NM_005186, NP_005177

UniProt: P07384

Pathways: Apoptosis