CAPNL1 antibody (AA 20-330)

Catalog No. ABIN3021623

The Rabbit Polyclonal anti-CAPNL1 antibody (ABIN3021623) specifically detects CAPNL1 in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for CAPNL1 antibody (AA 20-330) (ABIN3021623)

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CAPNL1 Antibody

Binding Specificity: AA 20-330

Sequence: KQRARELGLG RHENAIKYLG QDYEQLRVRC LQSGTLFRDE AFPPVPQSLG YKDLGPNSSK TYGIKWKRPT ELLSNPQFIV DGATRTDICQ GALGDCWLLA AIASLTLNDT LLHRVVPHGQ SFQNGYAGIF HFQLWQFGEW VDVVVDDLLP IKDGKLVFVH SAEGNEFWSA LLEKAYAKVN GSYEALSGGS TSEGFEDFTG GVTEWYELRK APSDLYQIIL KALERGSLLG CSIDISSVLD MEAITFKKLV KGHAYSVTGA KQVNYRGQVV SLIRMRNPWG EVEWTGAWSD SSSEWNNVDP YERDQLRVKM E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-330 of human Calpain 1 (NP_005177.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CAPNL1

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Alternative Name: CAPN1

Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.,CAPN1,CANP,CANP1,CANPL1,SPG76,muCANP,muCL,calpain 1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CAPN1

Molecular Weight: 81 kDa

Gene ID: 823

UniProt: P07384

Pathways: Apoptosis