PRTN3 antibody (N-Term)

Catalog No. ABIN2788703

Product Details anti-PRTN3 Antibody

Target: PRTN3 (Proteinase 3 (PRTN3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRTN3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IPQRLVNVVL GAHNVRTQEP TQQHFSVAQV FLNNYDAENK LNDVLLIQLS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PRTN3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRTN3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 256 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRTN3

Target: PRTN3 (Proteinase 3 (PRTN3))

Alternative Name: PRTN3 (PRTN3 Products)

Synonyms: ela2 antibody, MGC132250 antibody, ACPA antibody, AGP7 antibody, C-ANCA antibody, CANCA antibody, MBN antibody, MBT antibody, NP-4 antibody, NP4 antibody, P29 antibody, PR-3 antibody, PR3 antibody, mPR3 antibody, proteinase 3 L homeolog antibody, proteinase 3 antibody, prtn3.L antibody, PRTN3 antibody, Prtn3 antibody

Background: PRTN3 is a polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
Alias Symbols: ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP4, P29, PR-3, PR3
Protein Interaction Partner: Serpinb1a, SMAD3, IL32, SERPINB13, F2RL1, CAMP, ITGB2, SERPINA1, TNF, F2R, RELA, IL1B, ELN, SERPINB1, ITGAM,
Protein Size: 256

Molecular Weight: 28 kDa

Gene ID: 5657

NCBI Accession: NM_002777, NP_002768

UniProt: P24158