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IRAK4 antibody (C-Term)

IRAK4 Reactivity: Human, Rat, Cow, Horse, Sheep, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788803
  • Target See all IRAK4 Antibodies
    IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
    Binding Specificity
    • 37
    • 16
    • 15
    • 10
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 115
    • 67
    • 26
    • 15
    • 14
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Cow, Horse, Sheep, Guinea Pig
    Host
    • 109
    • 11
    • 1
    Rabbit
    Clonality
    • 107
    • 14
    Polyclonal
    Conjugate
    • 53
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This IRAK4 antibody is un-conjugated
    Application
    • 112
    • 52
    • 37
    • 26
    • 18
    • 16
    • 15
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS
    Predicted Reactivity
    Cow: 77%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rat: 91%, Sheep: 77%
    Characteristics
    This is a rabbit polyclonal antibody against IRAK4. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product IRAK4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 336 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
    Alternative Name
    IRAK4 (IRAK4 Products)
    Synonyms
    zgc:55553 antibody, IRAK4 antibody, ipd1 antibody, irak-4 antibody, ny-ran-64 antibody, ny-ren-64 antibody, ren64 antibody, irak4 antibody, IPD1 antibody, IRAK-4 antibody, NY-REN-64 antibody, REN64 antibody, 8430405M07Rik antibody, 9330209D03Rik antibody, interleukin 1 receptor associated kinase 4 antibody, interleukin-1 receptor-associated kinase 4 antibody, IRAK4 antibody, irak4 antibody, Irak4 antibody
    Background
    This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4
    Protein Interaction Partner: MYD88, IRAK1, IKBKG, SASH1, ARNT, TNFRSF13B, IL1RL1, TRAF6, PELI1, PELI2, IL1R1, MBP, HIST1H1A, HIST1H1T, HIST1H1B, HIST1H1E, HIST1H1D, HIST1H1C, EIF4EBP1, TIRAP, IRAK3, IRAK2, TLR4, TICAM2, TBPL1, PELI3, UBC,
    Protein Size: 336
    Molecular Weight
    36 kDa
    Gene ID
    51135
    NCBI Accession
    NM_001145256, NP_001138728
    Pathways
    NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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