IRAK4 antibody (Interleukin-1 Receptor-Associated Kinase 4) (C-Term)

Details for Product anti-IRAK4 Antibody No. ABIN2788803, Supplier: Log in to see
Antigen
  • zgc:55553
  • IRAK4
  • ipd1
  • irak-4
  • ny-ran-64
  • ny-ren-64
  • ren64
  • irak4
  • IPD1
  • IRAK-4
  • NY-REN-64
  • REN64
  • 8430405M07Rik
  • 9330209D03Rik
  • interleukin-1 receptor-associated kinase 4
  • Interleukin-1 receptor-associated kinase 4
  • IRAK4
  • irak4
  • LOC100227974
  • Irak4
Alternatives
anti-Human IRAK4 antibody for Immunoprecipitation
Epitope
C-Term
40
30
16
15
15
15
14
6
6
6
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Guinea Pig, Horse (Equine), Human, Rat (Rattus), Sheep (Ovine)
193
55
26
13
4
4
3
3
2
2
2
1
1
Host
Rabbit
144
33
24
Clonality
Polyclonal
Conjugate
This IRAK4 antibody is un-conjugated
9
8
7
6
5
5
4
3
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
152
90
27
26
26
11
11
9
7
5
3
2
2
1
1
1
Options
Supplier
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Supplier Product No.
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Blocking Peptide Blocking peptide for this product available: ABIN978590
Sequence TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS
Predicted Reactivity Cow: 77%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rat: 91%, Sheep: 77%
Characteristics This is a rabbit polyclonal antibody against IRAK4. It was validated on Western Blot.
Purification Affinity Purified
Alternative Name IRAK4 (IRAK4 Antibody Abstract)
Background This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4
Protein Interaction Partner: MYD88, IRAK1, IKBKG, SASH1, ARNT, TNFRSF13B, IL1RL1, TRAF6, PELI1, PELI2, IL1R1, MBP, HIST1H1A, HIST1H1T, HIST1H1B, HIST1H1E, HIST1H1D, HIST1H1C, EIF4EBP1, TIRAP, IRAK3, IRAK2, TLR4, TICAM2, TBPL1, PELI3, UBC,
Protein Size: 336
Molecular Weight 36 kDa
Gene ID 51135
NCBI Accession NM_001145256, NP_001138728
Research Area Immunology, Innate Immunity, Atherosclerosis, Cytokines, Receptors, Inflammation
Pathways NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 336 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) antibody (ABIN2788803) anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) antibody
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