LGI1 antibody (N-Term)
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- Target See all LGI1 Antibodies
- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
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Binding Specificity
- N-Term
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Reactivity
- Mouse, Human, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LGI1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LLSALLLTEG KKPAKPKCPA VCTCTKDNAL CENARSIPRT VPPDVISLSF
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against LGI1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product LGI1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 557 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
- Alternative Name
- LGI1 (LGI1 Products)
- Synonyms
- ADLTE antibody, ADPAEF antibody, ADPEAF antibody, EPITEMPIN antibody, EPT antibody, ETL1 antibody, IB1099 antibody, BB130740 antibody, MGC146600 antibody, LGIa antibody, fb78h12 antibody, wu:fb78h12 antibody, zgc:65886 antibody, leucine rich glioma inactivated 1 antibody, leucine-rich repeat LGI family, member 1 antibody, leucine-rich, glioma inactivated 1 antibody, leucine-rich, glioma inactivated 1b antibody, leucine-rich, glioma inactivated 1a antibody, LGI1 antibody, Lgi1 antibody, lgi1 antibody, lgi1b antibody, lgi1a antibody
- Background
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This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.
Alias Symbols: EPITEMPIN, EPT, ETL1, IB1099, ADLTE, ADPAEF
Protein Interaction Partner: ADAM22, DLG4,
Protein Size: 557 - Molecular Weight
- 61 kDa
- Gene ID
- 9211
- NCBI Accession
- NM_005097, NP_005088
- UniProt
- O95970
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