ATP6V1C2 antibody (C-Term)

Catalog No. ABIN2789107

Product Details anti-ATP6V1C2 Antibody

Target: ATP6V1C2 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C2 (ATP6V1C2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1C2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SEAFIAWIHI KALRVFVESV LRYGLPVNFQ AVLLQPHKKS STKRLREVLN

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ATP6V1C2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 381 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP6V1C2

Target: ATP6V1C2 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C2 (ATP6V1C2))

Alternative Name: ATP6V1C2 (ATP6V1C2 Products)

Synonyms: ATP6C2 antibody, VMA5 antibody, 1110038G14Rik antibody, ATPase H+ transporting V1 subunit C2 antibody, ATPase, H+ transporting, lysosomal V1 subunit C2 antibody, ATP6V1C2 antibody, Atp6v1c2 antibody

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
Alias Symbols: ATP6C2, VMA5
Protein Interaction Partner: GOLGA2,
Protein Size: 381

Molecular Weight: 42 kDa

Gene ID: 245973

NCBI Accession: NM_144583, NP_653184

UniProt: A8KA87

Pathways: Transition Metal Ion Homeostasis, Proton Transport