GADD45GIP1 antibody (Middle Region)
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- Target See all GADD45GIP1 Antibodies
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Pig, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GADD45GIP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SLRVKQLAEE QKRREREQHI AECMAKMPQM IVNWQQQQRE NWEKAQADKE
- Predicted Reactivity
- Cow: 90%, Dog: 90%, Guinea Pig: 85%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 91%
- Characteristics
- This is a rabbit polyclonal antibody against GADD45GIP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GADD45GIP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 222 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
- Alternative Name
- GADD45GIP1 (GADD45GIP1 Products)
- Synonyms
- si:dkey-194e13.6 antibody, CKBBP2 antibody, CRIF1 antibody, PLINP antibody, PLINP-1 antibody, PRG6 antibody, Plinp1 antibody, 2310040G17Rik antibody, AI425883 antibody, Crif1 antibody, growth arrest and DNA-damage-inducible, gamma interacting protein 1 antibody, GADD45G interacting protein 1 antibody, gadd45gip1 antibody, GADD45GIP1 antibody, Gadd45gip1 antibody
- Background
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GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. GADD45GIP1 acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. GADD45GIP1 may be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Alias Symbols: CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1, PRG6, Plinp1
Protein Interaction Partner: FBXW11, UBC, LIN28A, EXOSC4, UPF2, TMEM177, MRPL11, MRPL14, TSR1, PTRH2, EIF3C, TAP1, MRPL12, APP, COPS5, HNRNPA1, NFE2L2, ICT1, AR, IKBKG, GADD45G, GADD45B, NR4A1, GADD45A, CSNK2B,
Protein Size: 222 - Molecular Weight
- 24 kDa
- Gene ID
- 90480
- NCBI Accession
- NM_052850, NP_443082
- UniProt
- Q8TAE8
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