SLAMF1 antibody (Middle Region)

Catalog No. ABIN2789221

Product Details anti-SLAMF1 Antibody

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QVSPPEIKVL NKTQENENGT CSLLLACTVK KGDHVTYSWS DEAGTHLLSR

Predicted Reactivity: Cow: 77%, Dog: 85%, Goat: 77%, Guinea Pig: 80%, Horse: 85%, Human: 100%, Mouse: 87%, Pig: 100%, Rabbit: 80%, Rat: 93%, Sheep: 77%

Characteristics: This is a rabbit polyclonal antibody against Slamf1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Slamf1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: Slamf1 (SLAMF1 Products)

Synonyms: CD150 antibody, SLAM antibody, SLAMF1 antibody, 4933415F16 antibody, AA177906 antibody, CDw150 antibody, ESTM51 antibody, IPO-3 antibody, Slam antibody, RGD1560634 antibody, signaling lymphocytic activation molecule family member 1 antibody, SLAMF1 antibody, Slamf1 antibody

Background: Slamf1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Alias Symbols: 4933415F16, AA177906, CD150, CDw150, ESTM51, IPO-3, Slam
Protein Interaction Partner: Sh2d1b1, Sh2d1b2, Sh2d1a,
Protein Size: 343

Molecular Weight: 38 kDa

Gene ID: 27218

NCBI Accession: NM_013730, NP_038758

UniProt: Q9QUM4