PLAUR antibody (N-Term)
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- Target See all PLAUR Antibodies
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PLAUR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ELELVEKSCT HSEKTNRTLS YRTGLKITSL TEVVCGLDLC NQGNSGRAVT
- Predicted Reactivity
- Human: 100%, Mouse: 82%
- Characteristics
- This is a rabbit polyclonal antibody against PLAUR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of PLAUR
- Top Product
- Discover our top product PLAUR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 335 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Alternative Name
- PLAUR (PLAUR Products)
- Synonyms
- Cd87 antibody, u-PAR antibody, uPAR antibody, CD87 antibody, U-PAR antibody, UPAR antibody, URKR antibody, Par antibody, Plaur3 antibody, uPAR-2 antibody, uPAR-3 antibody, PLAUR antibody, plasminogen activator, urokinase receptor antibody, Plaur antibody, PLAUR antibody
- Background
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This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Alias Symbols: CD87, UPAR, URKR
Protein Interaction Partner: TEX101, PLAU, LYN, ELAVL1, VMA21, TXNDC17, SCAF4, SDHAF2, UBQLN2, WDHD1, SELENBP1, TBCA, PSAP, CTSA, OXCT1, NOTCH2, HDLBP, CTTN, LRP1B, SURF2, SRPX2, MMP12, IL6ST, FAP, KNG1, VTN, TYK2, PFN2, JAK1, HCK, FYN, ITGB1, EEF1A1, ITGAM, LRP1, IGF2R, ITGB2, PDGFR
Protein Size: 335 - Molecular Weight
- 37 kDa
- Gene ID
- 5329
- NCBI Accession
- NM_002659, NP_002650
- UniProt
- Q9GK80
- Pathways
- Inositol Metabolic Process
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