PMP22 antibody (N-Term)
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- Target See all PMP22 Antibodies
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
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Binding Specificity
- N-Term
- Reactivity
- Human, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PMP22 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QWIVGNGHAT DLWQNCSTSS SGNVHHCFSS SPNEWLQSVQ ATMILSIIFS
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rabbit: 100%, Rat: 93%, Sheep: 86%
- Characteristics
- This is a rabbit polyclonal antibody against PMP22. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of PMP22
- Top Product
- Discover our top product PMP22 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 160 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
- Alternative Name
- PMP22 (PMP22 Products)
- Synonyms
- CMT1A antibody, CMT1E antibody, DSS antibody, GAS-3 antibody, HMSNIA antibody, HNPP antibody, Sp110 antibody, 22kDa antibody, Gas-3 antibody, Tr antibody, trembler antibody, pmp22 antibody, wu:fa04d03 antibody, wu:fa08d03 antibody, MGC80653 antibody, PMP22 antibody, MGC69407 antibody, id:ibd2630 antibody, wu:fb81f09 antibody, zgc:136919 antibody, peripheral myelin protein 22 antibody, peripheral myelin protein 22a antibody, peripheral myelin protein 22 S homeolog antibody, peripheral myelin protein 22b antibody, PMP22 antibody, Pmp22 antibody, pmp22a antibody, pmp22.S antibody, pmp22 antibody, pmp22b antibody
- Background
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This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein.
Alias Symbols: CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, MGC20769, Sp110
Protein Interaction Partner: SMIM3, KLRC1, PEX19, DDX52, ELAVL1, MPZ, CANX,
Protein Size: 160 - Molecular Weight
- 18 kDa
- Gene ID
- 5376
- NCBI Accession
- NM_153321, NP_696996
- UniProt
- Q01453
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