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Desmoglein 1 antibody (C-Term)
DSG1
Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Desmoglein 1 Antibody
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Target
See all Desmoglein 1 (DSG1) Antibodies
Desmoglein 1 (DSG1)
Binding Specificity
All epitopes for Desmoglein 1 antibodies
C-Term
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Host
All hosts for Desmoglein 1 antibodies
Rabbit
Clonality
All clonalities for Desmoglein 1 antibodies
Polyclonal
Conjugate
All conjugates for Desmoglein 1 antibodies
This Desmoglein 1 antibody is un-conjugated
Application
All applications for Desmoglein 1 antibodies
Western Blotting (WB)
Sequence
GGIGLSSLGG TASIGHMRSS SDHHFNQTIG SASPSTARSR ITKYSTVQYS
Predicted Reactivity
Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
Characteristics
This is a rabbit polyclonal antibody against DSG1. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human DSG1
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Desmoglein 1
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Target
Desmoglein 1 (DSG1)
Alternative Name
DSG1 (DSG1 Products )
Synonyms
CDHF4 antibody, DG1 antibody, DSG antibody, PPKS1 antibody, SPPK1 antibody, DSG-1 antibody, DSG1 antibody, Dsg1b antibody, Dsg1c antibody, desmoglein 1 antibody, desmoglein 4 antibody, DSG1 antibody, DSG4 antibody, Dsg1 antibody
Background
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. Alias Symbols: DG1, DSG, CDHF4, EPKHE, PPKS1, SPPK1, EPKHIA Protein Size: 408
Molecular Weight
44 kDa
Gene ID
1828
NCBI Accession
NM_001942 , NP_001933
UniProt
B7Z845
Pathways
Cell-Cell Junction Organization
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