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DGAT1 antibody (N-Term)
DGAT1
Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Goat, Rabbit, Zebrafish (Danio rerio), Horse, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DGAT1 Antibody
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Target
See all DGAT1 Antibodies
DGAT1
(Diacylglycerol O-Acyltransferase 1 (DGAT1))
Binding Specificity
All epitopes for DGAT1 antibodies
N-Term
Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Goat, Rabbit, Zebrafish (Danio rerio), Horse, Guinea Pig
Host
All hosts for DGAT1 antibodies
Rabbit
Clonality
All clonalities for DGAT1 antibodies
Polyclonal
Conjugate
All conjugates for DGAT1 antibodies
This DGAT1 antibody is un-conjugated
Application
All applications for DGAT1 antibodies
Western Blotting (WB)
Sequence
HRLQDSLFSS DSGFSNYRGI LNWCVVMLIL SNARLFLENL IKYGILVDPI
Predicted Reactivity
Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
Characteristics
This is a rabbit polyclonal antibody against Dgat1. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Dgat1
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DGAT1
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Target
DGAT1
(Diacylglycerol O-Acyltransferase 1 (DGAT1))
Alternative Name
Dgat1 (DGAT1 Products )
Synonyms
ARAT antibody, ARGP1 antibody, DGAT antibody, C75990 antibody, D15Ertd23e antibody, Dgat antibody, dgat1 antibody, wu:fd36g11 antibody, zgc:77691 antibody, DGAT1 antibody, ABX45 antibody, AS11 antibody, ATDGAT antibody, DIACYLGLYCEROL ACYLTRANSFERASE antibody, F27F23.24 antibody, RDS1 antibody, TRIACYLGLYCEROL BIOSYNTHESIS DEFECT 1 antibody, DDBDRAFT_0202877 antibody, DDBDRAFT_0304727 antibody, DDB_0202877 antibody, DDB_0304727 antibody, zgc:92327 antibody, diacylglycerol O-acyltransferase 1 antibody, diacylglycerol O-acyltransferase 1a antibody, diacylglycerol O-acyltransferase 1 L homeolog antibody, membrane bound O-acyl transferase (MBOAT) family protein antibody, diacylglycerol O-acyltransferase Dga1 antibody, diacylglycerol O-acyltransferase 1b antibody, DGAT1 antibody, Dgat1 antibody, dgat1a antibody, dgat1.L antibody, TAG1 antibody, dgat1 antibody, MGYG_02131 antibody, Tsp_02502 antibody, LOC100283803 antibody, dga1 antibody, dgat1b antibody
Background
Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. Alias Symbols: C75990, D15Ertd23e, Dgat Protein Size: 498
Molecular Weight
57 kDa
Gene ID
13350
NCBI Accession
NM_010046 , NP_034176
UniProt
Q9Z2A7
Pathways
Hormone Transport
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