HRPT2 antibody (C-Term)
-
- Target See all HRPT2 (CDC73) Antibodies
- HRPT2 (CDC73) (Parafibromin (CDC73))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HRPT2 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- KFVPSDEKKK QGCQRENETL IQRRKDQMQP GGTAISVTVP YRVVDQPLKL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
- Characteristics
- This is a rabbit polyclonal antibody against CDC73. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CDC73 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 531 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- HRPT2 (CDC73) (Parafibromin (CDC73))
- Alternative Name
- CDC73 (CDC73 Products)
- Synonyms
- C1orf28 antibody, HPTJT antibody, HRPT2 antibody, HYX antibody, 8430414L16Rik antibody, BC027756 antibody, C130030P16Rik antibody, C81219 antibody, Hrpt2 antibody, hrpt2 antibody, zgc:63956 antibody, MGC108428 antibody, cdc73 antibody, LOC100222932 antibody, cell division cycle 73 antibody, cell division cycle 73, Paf1/RNA polymerase II complex component antibody, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antibody, parafibromin antibody, cell division cycle 73 S homeolog antibody, CDC73 antibody, Cdc73 antibody, cdc73 antibody, Tsp_03925 antibody, Tsp_04052 antibody, Tsp_04125 antibody, cdc73.S antibody
- Background
-
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma
Alias Symbols: C1orf28, FLJ23316, HPTJT, HRPT2, HYX
Protein Interaction Partner: CCDC155, FSD2, TSGA10, CEP70, VPS37B, MTUS2, UBC, TFCP2, GOLGA2, ALAS1, CIAO1, AURKB, GPRASP2, COG3, MYH14, MYL12A, ARFGEF2, NUP98, MYH9, CHUK, DNMT3B, DNMT3A, SOX2, BCL9L, PAF1, CTR9, TCF4, CTNNB1, LEO1, GTF2F1, SUV39H1, PTPN11, WDR61, HIST1H3A, RNF20, R
Protein Size: 531 - Molecular Weight
- 58 kDa
- Gene ID
- 79577
- NCBI Accession
- NM_024529, NP_078805
- UniProt
- Q6P1J9
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
-