ARTN antibody (Middle Region)
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- Target See all ARTN Antibodies
- ARTN (Artemin (ARTN))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARTN antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RTARWCSGRA RRPPPQPSRP APPPPAPPSA LPRGGRAARA GGPGSRARAA
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ARTN. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product ARTN Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 228 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ARTN (Artemin (ARTN))
- Alternative Name
- ARTN (ARTN Products)
- Synonyms
- ARTN antibody, ENOVIN antibody, EVN antibody, NBN antibody, neublastin antibody, artemin antibody, ARTN antibody, Artn antibody
- Background
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The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ENOVIN, EVN, NBN
Protein Interaction Partner: GFRA3, ARTN,
Protein Size: 228 - Molecular Weight
- 19 kDa
- Gene ID
- 9048
- NCBI Accession
- NM_057090, NP_476431
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