ARTN antibody (Middle Region)

Catalog No. ABIN2789666

Product Details anti-ARTN Antibody

Target: ARTN (Artemin (ARTN))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARTN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RTARWCSGRA RRPPPQPSRP APPPPAPPSA LPRGGRAARA GGPGSRARAA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ARTN. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 228 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARTN

Target: ARTN (Artemin (ARTN))

Alternative Name: ARTN (ARTN Products)

Synonyms: ARTN antibody, ENOVIN antibody, EVN antibody, NBN antibody, neublastin antibody, artemin antibody, ARTN antibody, Artn antibody

Background: The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ENOVIN, EVN, NBN
Protein Interaction Partner: GFRA3, ARTN,
Protein Size: 228

Molecular Weight: 19 kDa

Gene ID: 9048

NCBI Accession: NM_057090, NP_476431