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GIPR antibody (N-Term)
GIPR
Reactivity: Human, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GIPR Antibody
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Target
See all GIPR Antibodies
GIPR
(Gastric Inhibitory Polypeptide Receptor (GIPR))
Binding Specificity
All epitopes for GIPR antibodies
N-Term
Reactivity
All reactivities for GIPR antibodies
Human, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig, Pig
Host
All hosts for GIPR antibodies
Rabbit
Clonality
All clonalities for GIPR antibodies
Polyclonal
Conjugate
All conjugates for GIPR antibodies
This GIPR antibody is un-conjugated
Application
All applications for GIPR antibodies
Western Blotting (WB)
Sequence
LRLSLCGLLL QRAETGSKGQ TAGELYQRWE RYRRECQETL AAAEPPSVAA
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against GIPR. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human GIPR
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for GIPR
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Target
GIPR
(Gastric Inhibitory Polypeptide Receptor (GIPR))
Alternative Name
GIPR (GIPR Products )
Synonyms
GIPR antibody, PGQTL2 antibody, GIP-R antibody, Gm1081 antibody, Gm160 antibody, Gippr antibody, RATGIPPR antibody, gastric inhibitory polypeptide receptor antibody, glucagon receptor antibody, GIPR antibody, LOC100303705 antibody, Gipr antibody
Background
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. Alias Symbols: PGQTL2 Protein Size: 430
Molecular Weight
47 kDa
Gene ID
2696
NCBI Accession
NM_000164 , NP_000155
UniProt
B7WP14
Pathways
Positive Regulation of Peptide Hormone Secretion , cAMP Metabolic Process , Regulation of G-Protein Coupled Receptor Protein Signaling
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