Myotilin antibody (C-Term)
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- Target See all Myotilin (MYOT) Antibodies
- Myotilin (MYOT)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Myotilin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RNNEMVQFNT DRISLYQDNT GRVTLLIKDV NKKDAGWYTV SAVNEAGVTT
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MYOT. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MYOT Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 498 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Myotilin (MYOT)
- Alternative Name
- MYOT (MYOT Products)
- Synonyms
- LGMD1 antibody, LGMD1A antibody, MFM3 antibody, TTID antibody, TTOD antibody, 5530402I04Rik antibody, Ttid antibody, MYOT antibody, ttid antibody, myotilin antibody, MYOT antibody, Myot antibody, myot antibody
- Background
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This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: LGMD1, LGMD1A, TTID
Protein Interaction Partner: NME7, TRIM63, TRIM55, GPRASP2, TFG, AXIN1, APP, LRP12, MYOT, FLNA, ACTN1, FLNC, ST7,
Protein Size: 498 - Molecular Weight
- 55 kDa
- Gene ID
- 9499
- NCBI Accession
- NM_006790, NP_006781
- UniProt
- Q9UBF9
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