×
For best experience we recommend to activate Javascript in your browser.
UNC13D antibody (C-Term)
UNC13D
Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-UNC13D Antibody
(hide)
Target
See all UNC13D Antibodies
UNC13D
(Unc-13 Homolog D (UNC13D))
Binding Specificity
All epitopes for UNC13D antibodies
C-Term
Reactivity
Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse
Host
All hosts for UNC13D antibodies
Rabbit
Clonality
All clonalities for UNC13D antibodies
Polyclonal
Conjugate
All conjugates for UNC13D antibodies
This UNC13D antibody is un-conjugated
Application
All applications for UNC13D antibodies
Western Blotting (WB)
Sequence
SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
Predicted Reactivity
Cow: 92%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against UNC13D. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human UNC13D
Top Product
Discover our top product UNC13D Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for UNC13D
(hide)
Target
UNC13D
(Unc-13 Homolog D (UNC13D))
Alternative Name
UNC13D (UNC13D Products )
Synonyms
FHL3 antibody, HLH3 antibody, HPLH3 antibody, Munc13-4 antibody, UNC13D antibody, 2610108D09Rik antibody, Jinx antibody, mFLJ00067 antibody, Unc13h4 antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, unc-13 homolog D antibody, unc-13 homolog D (C. elegans) antibody, transforming growth factor beta induced antibody, UNC13D antibody, Unc13d antibody, TGFBI antibody, unc13d antibody, un13d antibody
Background
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4 Protein Interaction Partner: UBC, CUL5, VPS37B, XRN2, LMNA, RAB27B, RAB27A, Protein Size: 1090
Molecular Weight
119 kDa
Gene ID
201294
NCBI Accession
NM_199242 , NP_954712
UniProt
Q70J99
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process
Recently viewed
(hide)