UNC13D antibody (AA 7-172)

Catalog No. ABIN7166249

Product Details anti-UNC13D Antibody

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Binding Specificity: AA 7-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC13D antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein unc-13 homolog D protein (7-172AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UNC13D

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Alternative Name: UNC13D (UNC13D Products)

Synonyms: FHL3 antibody, HLH3 antibody, HPLH3 antibody, Munc13-4 antibody, UNC13D antibody, 2610108D09Rik antibody, Jinx antibody, mFLJ00067 antibody, Unc13h4 antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, unc-13 homolog D antibody, unc-13 homolog D (C. elegans) antibody, transforming growth factor beta induced antibody, UNC13D antibody, Unc13d antibody, TGFBI antibody, unc13d antibody, un13d antibody

Background:

Background: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.

Aliases: FHL 3 antibody, FHL3 antibody, FLJ00067 antibody, HLH 3 antibody, HLH3 antibody, HPLH 3 antibody, HPLH3 antibody, Jinx antibody, Munc13 4 antibody, Munc13-4 antibody, Protein unc 13 homolog D antibody, Protein unc-13 homolog D antibody, UN13D_HUMAN antibody, Unc 13 homolog D antibody, UNC 13D antibody, Unc-13 homolog D (C. elegans) antibody, Unc13 homolog D (C elegans) antibody, Unc13 homolog D antibody, UNC13, C. elegans, homolog of, D antibody, UNC13D antibody, Unc13h4 antibody

UniProt: Q70J99

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process