SOSTDC1 antibody (C-Term)

Catalog No. ABIN2789780

Product Details anti-SOSTDC1 Antibody

Target: SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOSTDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ITVVTACKCK RYTRQHNESS HNFESMSPAK PVQHHRERKR ASKSSKHSMS

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SOSTDC1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 206 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOSTDC1

Target: SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))

Alternative Name: SOSTDC1 (SOSTDC1 Products)

Synonyms: SOSTDC1 antibody, zgc:110293 antibody, DKFZp469J0531 antibody, Usag1 antibody, ECTODIN antibody, USAG1 antibody, 0610006G05Rik antibody, Sostl antibody, USAG-1 antibody, Wise antibody, ectodin antibody, WISE antibody, sclerostin domain containing 1 antibody, sclerostin domain containing 1a antibody, SOSTDC1 antibody, sostdc1a antibody, Sostdc1 antibody

Background: This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.
Alias Symbols: CDA019, DKFZp564D206, ECTODIN, USAG1
Protein Interaction Partner: SOSTDC1, CDC20, BMP7, BMP6, BMP4, BMP2,
Protein Size: 206

Molecular Weight: 21 kDa

Gene ID: 25928

NCBI Accession: NM_015464, NP_056279

UniProt: Q6X4U4