DMGDH antibody (C-Term)
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- Target See all DMGDH Antibodies
- DMGDH (Dimethylglycine Dehydrogenase (DMGDH))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DMGDH antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YVPVQLSEVG QQVEVELLGK NYPAVIIQEP LVLTEPTRNR LQKKGGKDKT
- Predicted Reactivity
- Horse: 92%, Human: 100%, Pig: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against DMGDH. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product DMGDH Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 866 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DMGDH (Dimethylglycine Dehydrogenase (DMGDH))
- Alternative Name
- DMGDH (DMGDH Products)
- Synonyms
- MGC132281 antibody, DMGDHD antibody, ME2GLYDH antibody, Me2GlyDH antibody, 1200014D15Rik antibody, AI787269 antibody, dimethylglycine dehydrogenase antibody, dimethylglycine dehydrogenase L homeolog antibody, D-amino-acid oxidase antibody, Dimethylglycine dehydrogenase antibody, glycine cleavage system protein T antibody, dimethylglycine dehydrogenase precursor antibody, DMGDH antibody, dmgdh.L antibody, dmgdh antibody, SAR11_1253 antibody, EAMY_RS27375 antibody, EAMY_RS33570 antibody, VDBG_06516 antibody, Sinme_2570 antibody, HALXA_RS03495 antibody, Dmgdh antibody
- Background
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This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.
Alias Symbols: DMGDHD, ME2GLYDH
Protein Size: 866 - Molecular Weight
- 91 kDa
- Gene ID
- 29958
- NCBI Accession
- NM_013391, NP_037523
- UniProt
- Q9UI17
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