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DMGDH antibody (Middle Region)
DMGDH
Reactivity: Human, Mouse, Rat, Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DMGDH Antibody
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Target
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DMGDH
(Dimethylglycine Dehydrogenase (DMGDH))
Binding Specificity
All epitopes for DMGDH antibodies
Middle Region
Reactivity
Human, Mouse, Rat, Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig
Host
All hosts for DMGDH antibodies
Rabbit
Clonality
All clonalities for DMGDH antibodies
Polyclonal
Conjugate
All conjugates for DMGDH antibodies
This DMGDH antibody is un-conjugated
Application
All applications for DMGDH antibodies
Western Blotting (WB)
Sequence
SELHDLRWIE EAAFRGGYDV EIQNITDEFG VLGVAGPYAR RVLQKLTSE
Predicted Reactivity
Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
Characteristics
This is a rabbit polyclonal antibody against Dmgdh. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of mouse DMGDH
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DMGDH
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Target
DMGDH
(Dimethylglycine Dehydrogenase (DMGDH))
Alternative Name
Dmgdh (DMGDH Products )
Synonyms
MGC132281 antibody, DMGDHD antibody, ME2GLYDH antibody, Me2GlyDH antibody, 1200014D15Rik antibody, AI787269 antibody, dimethylglycine dehydrogenase antibody, dimethylglycine dehydrogenase L homeolog antibody, D-amino-acid oxidase antibody, Dimethylglycine dehydrogenase antibody, glycine cleavage system protein T antibody, dimethylglycine dehydrogenase precursor antibody, DMGDH antibody, dmgdh.L antibody, dmgdh antibody, SAR11_1253 antibody, EAMY_RS27375 antibody, EAMY_RS33570 antibody, VDBG_06516 antibody, Sinme_2570 antibody, HALXA_RS03495 antibody, Dmgdh antibody
Background
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. Alias Symbols: DMGDHD, ME2GLYDH Protein Size: 869
Molecular Weight
93 kDa
Gene ID
29958
NCBI Accession
NM_013391 , NP_037523
UniProt
Q9UI17
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