SGPL1 antibody (C-Term)

Catalog No. ABIN2790344

Product Details anti-SGPL1 Antibody

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Dog, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IHFCITLLHA RKRVAIQFLK DIRESVTQIM KNPKAKTTGM GAIYGMAQTT

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against SGPL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SGPL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 568 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGPL1

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Alternative Name: SGPL1 (SGPL1 Products)

Synonyms: SGPL1 antibody, zgc:162153 antibody, AI428538 antibody, D10Xrf456 antibody, S1PL antibody, Spl antibody, SPL antibody, Spgl1 antibody, spl antibody, sphingosine-1-phosphate lyase 1 antibody, sphingosine-1-phosphate lyase 1 L homeolog antibody, sphingosine phosphate lyase 1 antibody, SGPL1 antibody, sgpl1.L antibody, sgpl1 antibody, Sgpl1 antibody

Background: SGPL1 cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. SGPL1 elevates stress-induced ceramide production and apoptosis.
Alias Symbols: FLJ13811, KIAA1252, SPL
Protein Interaction Partner: UBC, PPP6R1, EGFR, vpu, IQCB1, ELAVL1, TMEM173,
Protein Size: 568

Molecular Weight: 63 kDa

Gene ID: 8879

NCBI Accession: NM_003901, NP_003892

UniProt: O95470

Pathways: Platelet-derived growth Factor Receptor Signaling