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TTI2 antibody (N-Term)

TTI2 Reactivity: Human, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2790934
  • Target See all TTI2 Antibodies
    TTI2 (TELO2 Interacting Protein 2 (TTI2))
    Binding Specificity
    • 4
    • 1
    N-Term
    Reactivity
    Human, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    This TTI2 antibody is un-conjugated
    Application
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    THSLEQPWTT PRSREVAREV LTSLLQVTEC GSVAGFLHGE NEDEKGRLSV
    Predicted Reactivity
    Cow: 100%, Dog: 92%, Guinea Pig: 75%, Horse: 100%, Human: 100%, Pig: 92%, Rabbit: 75%
    Characteristics
    This is a rabbit polyclonal antibody against TTI2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTI2
    Top Product
    Discover our top product TTI2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 508 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TTI2 (TELO2 Interacting Protein 2 (TTI2))
    Alternative Name
    TTI2 (TTI2 Products)
    Synonyms
    C8orf41 antibody, TELO2 interacting protein 2 antibody, TTI2 antibody, Tti2 antibody
    Background
    TTI2 is a regulator of the DNA damage response (DDR). 'TTI2 is part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). 'TTI2, together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
    Alias Symbols: C8orf41
    Protein Interaction Partner: FUS, UBC, SUMO1, NEDD8, EGFR, ELAVL1, RPAP3, PIH1D1, RUVBL2, TELO2, TTI1, RUVBL1, PRKDC, HSP90AA1, HSPA4,
    Protein Size: 508
    Molecular Weight
    56 kDa
    Gene ID
    80185
    NCBI Accession
    NM_025115, NP_079391
    UniProt
    Q6NXR4
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