Cyclin G2 antibody (CCNG2) (N-Term)

Details for Product anti-CCNG2 Antibody No. ABIN2792163, Supplier: Log in to see
Antigen
  • MGC83944
  • cyclin-G2-like
  • cyclin G2
  • LOC100051425
  • ccng2
  • CCNG2
  • Ccng2
  • LOC100523979
Epitope
N-Term
15
15
10
7
4
3
3
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
45
18
18
1
1
Host
Rabbit
41
4
Clonality
Polyclonal
Conjugate
This Cyclin G2 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
30
19
13
5
4
1
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG2
Sequence MKDLGAEHLA GHEGVQLLGL LNVYLEQEER FQPREKGLSL IEATPENDNT
Predicted Reactivity Cow: 91%, Dog: 91%, Human: 100%, Mouse: 83%, Rat: 83%
Characteristics This is a rabbit polyclonal antibody against CCNG2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name CCNG2 (CCNG2 Antibody Abstract)
Background The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53 % identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.
Protein Interaction Partner: EFHC2, FAM208B, NRIP2, UBC, SKP2, SKP1, PPP2CA, PPP2R4, PPP2R5C, PPP2R5B,
Protein Size: 344
Molecular Weight 39 kDa
Gene ID 901
NCBI Accession NM_004354, NP_004345
UniProt Q16589
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 344 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Cyclin G2 (CCNG2) (N-Term) antibody (ABIN2792163) Host: Rabbit Target Name: CCNG2 Sample Tissue: Human 293T Antibody Dilution: 1.0ug/ml
Western Blotting (WB) image for anti-Cyclin G2 (CCNG2) (N-Term) antibody (ABIN2792163) WB Suggested Anti-CCNG2 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive C...
Background publications Bennin, Don, Brake, McKenzie, Rosenbaum, Ortiz, DePaoli-Roach, Horne: "Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest." in: The Journal of biological chemistry, Vol. 277, Issue 30, pp. 27449-67, 2002 (PubMed).