APBA1 antibody (N-Term)
-
- Target See all APBA1 Antibodies
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
-
Binding Specificity
- N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This APBA1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- PPQQQHYVGR HQRGRALEDL RAQLGQEEEE RGECLARSAS TESGFHNHTD
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against APBA1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1
- Top Product
- Discover our top product APBA1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 837 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
- Alternative Name
- APBA1 (APBA1 Products)
- Synonyms
- APBA1 antibody, 6430513E09Rik antibody, Lin-10 antibody, Mint antibody, Mint1 antibody, Urop11 antibody, X11 antibody, X11alpha antibody, D9S411E antibody, LIN10 antibody, MINT1 antibody, X11A antibody, X11ALPHA antibody, amyloid beta precursor protein binding family A member 1 antibody, amyloid beta (A4) precursor protein-binding, family A, member 1b antibody, ketopantoate reductase antibody, 2-dehydropantoate 2-reductase antibody, amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) antibody, amyloid beta (A4) precursor protein-binding, family A, member 1 antibody, amyloid beta (A4) precursor protein binding, family A, member 1 antibody, APBA1 antibody, apba1b antibody, apbA1 antibody, apba1 antibody, Apba1 antibody
- Background
-
APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Alias Symbols: D9S411E, MINT1, X11, X11A, X11ALPHA, LIN10
Protein Interaction Partner: STXBP1, CNTNAP4, NRXN1, CNTNAP3, KIF17, LIN7B, KCNJ12, CCS, CACNA1B, HTR2C, CASK, NOTCH1, STX1A, APP, PSEN1, LIN7A, PSEN2, LIN7C, DLG1, APBB1,
Protein Size: 837 - Molecular Weight
- 93 kDa
- Gene ID
- 320
- NCBI Accession
- NM_001163
- UniProt
- Q02410
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
-