TCEB3 antibody (C-Term)
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- Target See all TCEB3 Antibodies
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
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Binding Specificity
- C-Term
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Reactivity
- Rat, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCEB3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- AYDGPSTSSA HLAPVVSSTV SYDPRKPTVK KIAPMMAKTI KAFKNRFSRR
- Cross-Reactivity
- Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
- Predicted Reactivity
- Dog: 100%, Guinea Pig: 91%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against TCEB3. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TCEB3
- Top Product
- Discover our top product TCEB3 Primary Antibody
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- Application Notes
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WB Suggested Anti-TCEB3 Antibody Titration: 7.5 µg/mL
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 772 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
- Alternative Name
- TCEB3 (TCEB3 Products)
- Synonyms
- CG6755 antibody, Dmel\\CG6755 antibody, Elo-A antibody, dEloA antibody, tceb3a antibody, zgc:56638 antibody, wu:fw66g10 antibody, TCEB3 antibody, 110kDa antibody, AA408125 antibody, Tceb3a antibody, El antibody, EloA antibody, SIII antibody, SIII p110 antibody, TCEB3A antibody, Elongin A antibody, transcription elongation factor B polypeptide 3 antibody, elongin A antibody, calcium binding and coiled-coil domain 1b antibody, elongin A S homeolog antibody, transcription elongation factor B subunit 3 antibody, EloA antibody, LOC413407 antibody, eloa antibody, calcoco1b antibody, ELOA antibody, eloa.S antibody, Eloa antibody, TCEB3 antibody
- Background
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Elongin A (TCEB3), which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Alias Symbols: EloA, SIII, TCEB3A, SIII p110
Protein Interaction Partner: KRTAP10-3, CEP57L1, SPERT, FAM9B, KRT40, CEP70, GMCL1, HOMEZ, TRIM54, MID2, PLK4, JAKMIP2, PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, MDFI, UBC, RAD54B, MED26, ECT2, BARD1, CDK12, TCEB2, TCEB1, B
Protein Size: 772 - Molecular Weight
- 87 kDa
- Gene ID
- 6924
- NCBI Accession
- NM_003198, NP_003189
- UniProt
- Q14241
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