HOXA10 antibody (Middle Region)
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- Target See all HOXA10 Antibodies
- HOXA10 (Homeobox A10 (HOXA10))
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Binding Specificity
- Middle Region
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Reactivity
- Mouse, Dog, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HOXA10 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GDEEAHASSS AAEELSPAPS ESSKASPEKD SLGNSKGENA ANWLTAKSGR
- Cross-Reactivity
- Dog (Canine), Chicken, Human, Mouse (Murine), Rabbit, Rat (Rattus)
- Predicted Reactivity
- Dog: 100%, Mouse: 92%, Rabbit: 100%
- Characteristics
- This is a rabbit polyclonal antibody against HOXA10. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HOXA10
- Top Product
- Discover our top product HOXA10 Primary Antibody
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- Application Notes
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WB Suggested Anti-HOXA10 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 393 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells." in: Leukemia research, Vol. 32, Issue 6, pp. 962-71, (2008) (PubMed).
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HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells." in: Leukemia research, Vol. 32, Issue 6, pp. 962-71, (2008) (PubMed).
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- Target
- HOXA10 (Homeobox A10 (HOXA10))
- Alternative Name
- HOXA10 / HOX1H (HOXA10 Products)
- Synonyms
- HOX1 antibody, HOX1.8 antibody, HOX1H antibody, PL antibody, Hox-1.8 antibody, Hoxa-10 antibody, HOXA10 antibody, Xhoxa9 antibody, hoxa10 antibody, hoxa9-A antibody, Hox-A10 antibody, z-140 antibody, Hoxa10 antibody, RGD1564605 antibody, RGD1566402 antibody, homeobox A10 antibody, homeobox A10 L homeolog antibody, homeobox A10b antibody, homeobox A11 antibody, HOXA10 antibody, Hoxa10 antibody, hoxa10.L antibody, hoxa10b antibody, Hoxa11 antibody
- Background
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA10 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: HOX1, HOX1.8, HOX1H, MGC12859, PL
Protein Interaction Partner: SPI1, COPS5, CREBBP, PBX1, SNAPC1, EMX1, POLR3D, SIRT2, GMNN, EP300, MEIS1, PTPN6, HOXA10, FOXO1,
Protein Size: 393 - Molecular Weight
- 40 kDa
- Gene ID
- 3206
- NCBI Accession
- NM_018951, NP_061824
- UniProt
- P31260
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