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KDM5A antibody (AA 101-200) (Alexa Fluor 594)

KDM5A Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 594
Catalog No. ABIN2803556
  • Target See all KDM5A Antibodies
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Binding Specificity
    • 14
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 101-200
    Reactivity
    • 68
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 61
    • 6
    Rabbit
    Clonality
    • 54
    • 14
    Polyclonal
    Conjugate
    • 27
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KDM5A antibody is conjugated to Alexa Fluor 594
    Application
    • 47
    • 25
    • 17
    • 13
    • 12
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KDM5A
    Isotype
    IgG
    Top Product
    Discover our top product KDM5A Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Alternative Name
    KDM5A (KDM5A Products)
    Synonyms
    Jarid1a antibody, JARID1A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, AA409370 antibody, C76986 antibody, Rbbp2 antibody, lysine demethylase 5A antibody, lysine (K)-specific demethylase 5A antibody, Kdm5a antibody, KDM5A antibody
    Background

    Synonyms: RBP2, RBBP2, RBBP-2, Lysine-specific demethylase 5A, Histone demethylase JARID1A, Jumonji/ARID domain-containing protein 1A, Retinoblastoma-binding protein 2, KDM5A, JARID1A

    Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity).

    Gene ID
    5927
    UniProt
    P29375
    Pathways
    Chromatin Binding, Warburg Effect
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