DLK1 antibody (delta-Like 1 Homolog (Drosophila)) (FITC)

Details for Product anti-DLK1 Antibody No. ABIN2853604, Supplier: Log in to see
Antigen
  • DLK
  • DLK-1
  • Delta1
  • FA1
  • PREF1
  • Pref-1
  • ZOG
  • pG2
  • AW742678
  • DlkI
  • Ly107
  • Peg9
  • SCP1
  • pref-1
  • Zog
  • delta-like 1 homolog (Drosophila)
  • DLK1
  • Dlk1
Reactivity
Mouse (Murine)
139
76
39
2
1
1
1
1
Host
Rat
100
57
20
1
Clonality (Clone)
Monoclonal ()
Conjugate
This DLK1 antibody is conjugated to FITC
8
7
6
6
6
5
5
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
123
77
71
22
13
9
7
6
3
2
2
1
1
Options
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Immunogen Pref-1-Fc protein
Clone 24-11-14
Isotype IgG1
Specificity This antibody reacts with Dlk.
Cross-Reactivity (Details) Species reactivity (tested):Mouse.
Purification Protein G Agarose Chromatography of hybridoma supernatant
Alternative Name DLK1 (DLK1 Antibody Abstract)
Background Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2
Gene ID 13386
NCBI Accession NP_034182
UniProt Q09163
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS, 0.09 % Sodium Azide, 1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 2-8 °C.
Supplier Images
Flow Cytometry (FACS) image for anti-DLK1 antibody (delta-Like 1 Homolog (Drosophila))  (FITC) (ABIN2853604) anti-delta-Like 1 Homolog (Drosophila) (DLK1) antibody (FITC)
Background publications Suzuki, Tanaka, Watanabe, Saito, Nonaka, Miyajima: "p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver." in: Gastroenterology, Vol. 135, Issue 1, pp. 270-281.e3, 2008 (PubMed).

Tanimizu, Nishikawa, Saito, Tsujimura, Miyajima: "Isolation of hepatoblasts based on the expression of Dlk/Pref-1." in: Journal of cell science, Vol. 116, Issue Pt 9, pp. 1775-86, 2003 (PubMed).

Kaneta, Osawa, Sudo, Nakauchi, Farr, Takahama: "A role for pref-1 and HES-1 in thymocyte development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 1, pp. 256-64, 2000 (PubMed).