ARG2 antibody (Center)
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- Target See all ARG2 Antibodies
- ARG2 (Arginase, Type II (ARG2))
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Binding Specificity
- Center
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARG2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit Polyclonal antibody to Arginase II (arginase, type II)
Arginase II antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ARG2. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product ARG2 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: mouse kidney , 293T cytoplasm extract , NT2D1
Validation: Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.32 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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L-Norvaline, a new therapeutic agent against Alzheimer's disease." in: Neural regeneration research, Vol. 14, Issue 9, pp. 1562-1572, (2019) (PubMed).
: "L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease." in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 4, pp. 1036-1054, (2019) (PubMed).
: "
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L-Norvaline, a new therapeutic agent against Alzheimer's disease." in: Neural regeneration research, Vol. 14, Issue 9, pp. 1562-1572, (2019) (PubMed).
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- Target
- ARG2 (Arginase, Type II (ARG2))
- Alternative Name
- arginase 2 (ARG2 Products)
- Synonyms
- AII antibody, AU022422 antibody, zgc:65793 antibody, zgc:85630 antibody, wu:fb67g02 antibody, ARG2 antibody, LeARG2 antibody, arg1 antibody, arg3 antibody, arg2 antibody, arg2-c antibody, arg2-b antibody, arginase 2 antibody, arginase type II antibody, arginase 2 L homeolog antibody, arginase 2 S homeolog antibody, ARG2 antibody, Arg2 antibody, arg2 antibody, arg2.L antibody, arg2.S antibody
- Background
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Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
Cellular Localization: Mitochondrion - Molecular Weight
- 39 kDa
- Gene ID
- 384
- UniProt
- P78540
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