TIMM17A antibody (C-Term)

Catalog No. ABIN2856587

Product Details anti-TIMM17A Antibody

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM17A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit polyclonal antibody to Tim17 (translocase of inner mitochondrial membrane 17 homolog A (yeast))
TIM17 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TIM17. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-TIMM17A antibody (ABIN2856587)

Sprenger, Wani, Hesseling, König, Patron, MacVicar, Ahola, Wai, Barth, Rugarli, Bergami, Langer: "Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy." in: EMBO molecular medicine, Vol. 11, Issue 1, (2019) (PubMed).

Target Details for TIMM17A

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Alternative Name: translocase of inner mitochondrial membrane 17A (TIMM17A Products)

Synonyms: TIM17 antibody, TIM17A antibody, Tim17 antibody, Timm17 antibody, 17kDa antibody, mTim17a antibody, translocase of inner mitochondrial membrane 17A antibody, translocase of inner mitochondrial membrane 17a antibody, TIMM17A antibody, Timm17a antibody

Background: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

Cellular Localization: Mitochondrion inner membrane, Multi-pass membrane protein

Molecular Weight: 18 kDa

Gene ID: 10440

UniProt: Q99595