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SART1 antibody (C-Term)

SART1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856790
  • Target See all SART1 Antibodies
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    Binding Specificity
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 32
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    • 1
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SART1 antibody is un-conjugated
    Application
    • 30
    • 13
    • 13
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio), Cow (Bovine)
    Cross-Reactivity (Details)
    Mouse (99 %), Rat (99 %), Xenopus laevis (89 %), Zebrafish (81 %), Bovine (99 %)
    Characteristics
    Rabbit polyclonal antibody to SART1 (squamous cell carcinoma antigen recognized by T cells)
    SART1 antibody [C1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human SART1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product SART1 Primary Antibody
  • Application Notes
    Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*
    Comment

    Positive Control: H1299 , HeLa , HepG2 , Molt-4 , Raji

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    Alternative Name
    SART1 (SART1 Products)
    Synonyms
    Dmel\\CG6686 antibody, SART1 antibody, MGC53679 antibody, MGC132129 antibody, zgc:91927 antibody, Ara1 antibody, HOMS1 antibody, SART1259 antibody, SNRNP110 antibody, Snu66 antibody, U5-110K antibody, CG6686 gene product from transcript CG6686-RB antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 antibody, squamous-cell carcinoma T-cell-recognized antigen antibody, squamous cell carcinoma antigen recognized by T cells 1 antibody, CG6686 antibody, sart1.S antibody, sart1 antibody, SART1 antibody, Sart1 antibody
    Background
    This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

    Cellular Localization: Nucleus
    Molecular Weight
    90 kDa
    Gene ID
    9092
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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