IL-1 beta antibody

Catalog No. ABIN285823

This Rabbit Polyclonal antibody specifically detects IL-1 beta in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for IL-1 beta antibody (ABIN285823)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IL-1 beta Antibody

Cross-Reactivity (Details): Specific for Natural and recombinant human IL-1ß. Has shown cross reactivity with primate and mouse IL-1ß1.1 mg/ml

Immunogen: IL1 b antibody was raised in rabbit using recombinant human IL-1 as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in PBS, carrier and preservative free.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL1b

Background: Interleukin-1 beta (IL-1Beta) also known as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene. IL-1Beta precursor is cleaved by caspase 1 (interleukin 1 beta convertase). Cytosolic thiol protease cleaves the product to form mature IL-1Beta.

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome