SLC25A14 antibody
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- Target See all SLC25A14 Antibodies
- SLC25A14 (Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14 (SLC25A14))
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC25A14 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Cross-Reactivity (Details)
- UCP5 may be alternatively spliced to produced at least 3 transcripts: UCP5L has a unique 22-aa unique N-terminal sequence, UCP5S is missing 3 aa (23-25 aa) and UCP5S has 31 aa insertion between TM II-IV. The UCP5 sequence is conserved in all 3 isoforms in rat and mouse UCP5. It is 94 % conserved in human UCP5/BMCP1. UCP5 has no appreciable homology with UCP1-4.
- Purification
- Affinity chromatography purified
- Immunogen
- UCP5 antibody was raised in rabbit using a 16 amino acid peptide from rat UCP5 as the immunogen.
- Isotype
- IgG
- Top Product
- Discover our top product SLC25A14 Primary Antibody
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- Application Notes
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ELISA: 1:10,000-1:100,000, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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UCP5Blocking Peptide, catalog no. 30R-AU004, is also available for use as a blocking control in assays to test for specificity of thisUCP5 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in PBS to a concentration of 1 mg/mL. Do not dilute further until ready to use.
- Concentration
- Lot specific
- Buffer
- Affinity purified IgG lyophilized from PBS with 0.1 % BSA, and 0.05 % NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- SLC25A14 (Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14 (SLC25A14))
- Alternative Name
- UCP5 (SLC25A14 Products)
- Synonyms
- ATPUMP5 antibody, DIC1 antibody, DICARBOXYLATE CARRIER 1 antibody, F14M13.10 antibody, F14M13_10 antibody, PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 5 antibody, uncoupling protein 5 antibody, zgc:55596 antibody, BMCP1 antibody, UCP5 antibody, BMCP-1 antibody, Ucp5 antibody, UCP5L antibody, UCP5S antibody, Bmcp1 antibody, solute carrier family 25 member 14 antibody, uncoupling protein 5 antibody, solute carrier family 25 (mitochondrial carrier, brain), member 14 antibody, SLC25A14 antibody, UCP5 antibody, slc25a14 antibody, Slc25a14 antibody
- Background
- Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. UCP5 or Brain Mitochondrial Carrier Protein 1 or BMCP1 (human 322 aa, chromosome Xq24, ~35% identity with UCP1-3) is mainly expressed in the brain and testis.
- Pathways
- Proton Transport
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