CCRD6 (Extracellular Domain), (N-Term) antibody

Catalog No. ABIN289391

Product Details

Target: CCRD6

Binding Specificity: Extracellular Domain, N-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Western Blotting (WB)

Cross-Reactivity (Details): Peptide sequence is <50% identical to other chemokine receptors in this regoin and cross-reactivity to mouse CCR D6 was .

Purification: Purified

Immunogen: CCRD6 antibody was raised in goat using a synthetic peptide C-L10 ATEDADSENSSFYYYDYLDEVAFM30 corresponding to the N-terminal extracellular domain of human D6 as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:50,000, FC: 2-4 µL/10^6 cells/50-104 µL, IHC: 1:125, WB: 1:500
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity urified and supplied in 10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.

Target Details

Target: CCRD6

Background: CCRD6 is a beta chemokine receptor similar to G protein-coupled receptors. Chemokines and the receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unkown.