PER3 antibody

Catalog No. ABIN289981

Product Details anti-PER3 Antibody

Target: PER3 (Period Homolog 3 (PER3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: ProteinG Affinity Purified

Immunogen: GST-Human PERIOD3 fusion Protein

Application Details

Restrictions: For Research Use only

Handling

Concentration: 1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for PER3

Target: PER3 (Period Homolog 3 (PER3))

Alternative Name: PERIOD3 (PER3 Products)

Synonyms: period3 antibody, rper3 antibody, GIG13 antibody, 2810049O06Rik antibody, mPer3 antibody, period circadian clock 3 antibody, period circadian regulator 3 antibody, Per3 antibody, PER3 antibody

Background: Most organisms show circadian 24-h rhythmicity in their behavior and phsysiology. In mammals,biological clock is located in the suprachiasmatic nucleus (SCN), generates circadian rhythms in behaviourand physiology. These biological rhythms are adjusted daily to the environmental light/dark cycle via theretinohypothalamic tract (RHT). Three mammalian priod genes (per1, per2, and per3) that resemble theclock-regulating gene of Dorosophia melangaster, period (per ), have been cloned. Circadian clocks arealso located in peripheral tissues of mammals that are synchronized by the SCN. A molecular description ofthe mammalian circadian system has revealed that circadian oscillations may be a fundamental property ofmany cells in the body.Recently, it has been shown that the phosphorylation of PER proteins by casein kinase Iepsilon can modulatethe nuclear localization of mPER1 and mPER3 but not of mPER2.This antibody is useful tool to clarify molecular functions that regulate biological clock.