ATP1B3 antibody

Catalog No. ABIN290059

Product Details anti-ATP1B3 Antibody

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATP1B3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Purification: Protein G

Immunogen: human cancer cel line

Clone: 5G10

Isotype: IgG2a kappa

Application Details

Application Notes: WB Not tested. IHC 5.0-10.0 ug/ml. ICC Not tested. ELISA Not tested. FCM 0.5-1.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for ATP1B3

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Alternative Name: CD298 (Na/K-ATPase b3) (ATP1B3 Products)

Synonyms: ATPB-3 antibody, CD298 antibody, AA409958 antibody, AI664000 antibody, AW212096 antibody, NKAB3S antibody, atp1b3 antibody, cb714 antibody, fb13c07 antibody, wu:fb13c07 antibody, cb713 antibody, nakatpb antibody, wu:fa14a07 antibody, ATPase Na+/K+ transporting subunit beta 3 antibody, ATPase, Na+/K+ transporting, beta 3 polypeptide antibody, ATPase Na+/K+ transporting subunit beta 3 S homeolog antibody, ATPase, Na+/K+ transporting, beta 3b polypeptide antibody, ATPase, Na+/K+ transporting, beta 3a polypeptide antibody, ATP1B3 antibody, Atp1b3 antibody, atp1b3.S antibody, atp1b3b antibody, atp1b3a antibody

Background: Na/K-ATPase is a membrane-associated enzyme responsible for the active transport of Na + and K+, and the maintenance of Na+ and K+ gradients across membrane. It is a heterodimer of two different kinds subunit, a large alpha subunit and a smaller glycoprotein subunit beta. At least four distinct alpha subunits and four beta subunit isoforms have been identified. In some tissues, it has been showed that Na/K-ATPase is associated with third subunit gamma, a small regulatory protein. CD298 (also known as Na/K-ATPase beta3) is a 42-kDa glycoprotein and one of beta subunit isoforms. CD298 has been detected in amphibians, mouse, rat,and human. In rat, CD298 expresses in a variety of tissues including testis, brain, kidney, spleen, stomach, small intestine, colon, lung, and liver. In theretina Na/K-ATPase restores Na+ and K+ gradients used by photoreceptor dark current, synaptic activity, action potential, and CD298 is largely restricted to photoreceptors in the mouse and rat. In human, CD298 also involves in regulation of T and B lymphocyte proliferation.This antibody is specific to human CD298 and will be useful for FCM, immunoprecipitation, immunohistochemistry.

Pathways: Thyroid Hormone Synthesis