IL-17 antibody
-
- Target See all IL-17 (IL17) Antibodies
- IL-17 (IL17) (Interleukin 17 (IL17))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This IL-17 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Functional Studies (Func)
- Specificity
- Recognizes human IL-17 (Interleukin-17/17A), a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
- Purification
- Purified
- Immunogen
-
Recombinant human IL-17.
Type of Immunogen: Recombinant protein - Isotype
- IgG
- Top Product
- Discover our top product IL17 Primary Antibody
-
-
- Application Notes
-
Approved: ELISA (0.5 - 2 μg/mL), Func (0.93 - 1.3 μg/mL), WB (0.1 - 0.2 μg/mL)
Usage: ELISA: May be used in an indirect ELISA or as the capture reagent in a sandwich ELISA. Western Blot: May be used under either reducing or non-reducing conditions. - Comment
-
Target Species of Antibody: Human
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.
- Concentration
- Lot specific
- Buffer
- Lyophilized, PBS, pH 7.4.
-
- Target
- IL-17 (IL17) (Interleukin 17 (IL17))
- Alternative Name
- IL17 (IL17 Products)
- Synonyms
- CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
- Background
-
Name/Gene ID: IL17
Synonyms: IL17
-