CD38 antibody (PerCP)
| Antigen |
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| Synonyms |
T10 |
| Clonality |
Monoclonal (HIT2) |
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Host
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Reactivity
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Conjugate
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FITC (32), PE (30), Biotin (26), APC (16), Cy5,PE (8), RPE (7), SPRD (4), Alexa Fluor 488 (3), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy7,PE (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,DY590 (2), PE,DY647 (2), Alexa Flour 488 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy7 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), Pacific Blue (1), RBITC (1), RPE,Cy5 (1)
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Application
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Flow Cytometry (FACS) (217), Immunohistochemistry (Frozen Sections) (IHC (fro)) (53), Immunoprecipitation (IP) (37), Immunofluorescence (IF) (33), Western Blotting (WB) (30), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (17), Immunohistochemistry (IHC) (13), ELISA (8), Blocking Antibody (Inhibition) (5), Immunocytochemistry (ICC) (4), Enzyme Immunoassay (EIA) (2), Functional Studies (Func) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN302055 |
| Quantity |
100 tests |
| Price |
377.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business Days |
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Immunogen
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Human thymocytes in foetus
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Isotype
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IgG1
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Clone
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HIT2
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Description
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CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induceactivation, proliferation and differentiation of mature lymphocytes and mediate apoptosis ofmyeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymaticactivity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ intoADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thusaffecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as animportant second messenger of neutrophil and dendritic cell migration.
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Specificity
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The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoproteinstrongly expressed mainly on plasma cells and activated T and B lymphocytes, it is anantigenic marker of lymphoid cells.HLDA III, WS Code T 155
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Application Notes
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The reagent is designed for Flow Cytometry analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 10 6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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Buffer
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The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azideand 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
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Storage
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Store in the dark at 2-8 o C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.Short-term exposure to room temperature should not affect the quality of the reagent.However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
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Research Area
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CD Antigens, Surface Receptors of Immune Cells
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Restrictions
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For Research Use only
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Alternatives for antigen "CD38", type "Antibodies"
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Hosts
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Mouse (129), Rat (86), Rabbit (28)
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Reactivities
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Human (151), Mouse (Murine) (95), Rat (Rattus) (7), Cow (Bovine) (1), Horse (Equine) (1), Pig (Porcine) (1), Rabbit (1)
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Applications
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Flow Cytometry (FACS) (217), Immunohistochemistry (Frozen Sections) (IHC (fro)) (53), Immunoprecipitation (IP) (37), Immunofluorescence (IF) (33), Western Blotting (WB) (30), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (17), Immunohistochemistry (IHC) (13), ELISA (8), Blocking Antibody (Inhibition) (5), Immunocytochemistry (ICC) (4), Enzyme Immunoassay (EIA) (2), Functional Studies (Func) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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FITC (32), PE (30), Biotin (26), APC (16), Cy5,PE (8), RPE (7), SPRD (4), Alexa Fluor 488 (3), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy7,PE (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,DY590 (2), PE,DY647 (2), Alexa Flour 488 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy7 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), Pacific Blue (1), RBITC (1), RPE,Cy5 (1)
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Epitopes
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C-Term (1)
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Alternatives 
