CPI-17 antibody (N-Term)

Catalog No. ABIN302213

Product Details anti-CPI-17 Antibody

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Binding Specificity: AA 1-147, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CPI-17 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects PPP1R14A.

Characteristics: Synonyms: Protein phosphatase 1 regulatory subunit 14A, CPI-17, CPI17, PPP1INL, 17 kDaPKC-potentiated inhibitory protein of PP1

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human PPP1R14A (1-147aa) purified from E. coli

Clone: 4H10

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western blot: 1: 250 approx. 1: 1000 (1: 500 as startin dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Alternative Name: PPP1R14A (PPP1R14A Products)

Synonyms: MGC81874 antibody, cpi-17 antibody, ppp1inl antibody, CPI-17 antibody, im:7147597 antibody, ppp1r14a antibody, zgc:110700 antibody, PPP1R14A antibody, CPI17 antibody, PPP1INL antibody, Cpi17 antibody, 1110001M11Rik antibody, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog antibody, protein phosphatase 1 regulatory inhibitor subunit 14A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14A antibody, ppp1r14a.L antibody, ppp1r14a antibody, ppp1r14aa antibody, PPP1R14A antibody, Ppp1r14a antibody

Background: PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization.Synonyms: 17 kDa PKC-potentiated inhibitory protein of PP1, CPI-17, CPI17, PPP1INL, Protein phosphatase 1 regulatory subunit 14A

Gene ID: 94274

UniProt: Q96A00