CPI-17 antibody

Catalog No. ABIN7138212

Product Details anti-CPI-17 Antibody

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPI-17 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa.36~40 (R-V-T-V-K) derived from Human CPI17a.

Isotype: IgG

Application Details

Application Notes: IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Alternative Name: PPP1R14A (PPP1R14A Products)

Synonyms: MGC81874 antibody, cpi-17 antibody, ppp1inl antibody, CPI-17 antibody, im:7147597 antibody, ppp1r14a antibody, zgc:110700 antibody, PPP1R14A antibody, CPI17 antibody, PPP1INL antibody, Cpi17 antibody, 1110001M11Rik antibody, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog antibody, protein phosphatase 1 regulatory inhibitor subunit 14A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14A antibody, ppp1r14a.L antibody, ppp1r14a antibody, ppp1r14aa antibody, PPP1R14A antibody, Ppp1r14a antibody

Background:

Background: Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

Hagerty L, et al. (2007) J Biol Chem. 2007, 282(7):4884-93
Seok YM, et al. (2008) J Pharmacol Exp Ther.
Niiro N et al. (2003) Biochem J. 2003 ,369(Pt 1):117-28

Aliases: 17 kDa PKC-potentiated inhibitory protein of PP1 antibody, 17-KDa protein antibody, 17 kDa PKC potentiated inhibitory protein of PP1 antibody, CPI 17 alpha antibody, CPI 17 antibody, CPI 17alpha antibody, CPI-17 antibody, CPI17 alpha antibody, CPI17 antibody, PKC potentiated inhibitory protein of PP1 antibody, PKC potentiated inhibitory protein of PP1, 17-KD antibody, PP14A_HUMAN antibody, PPP1INL antibody, Ppp1r14a antibody, Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD antibody, Protein kinase C-potentiated inhibitor protein of 17 kDa antibody, Protein phosphatase 1 antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 14A antibody, Protein phosphatase 1 regulatory subunit 14A antibody, Regulatory subunit 14A antibody

UniProt: Q96A00