CHRM3 antibody (Cytoplasmic Domain)
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- Target See all CHRM3 Antibodies
- CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))
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Binding Specificity
- Cytoplasmic Domain
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHRM3 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects Muscarinic Acetylcholine Receptor M3 (CHRM3).
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Immunoaffinity Chromatography
- Immunogen
- CHRM3 antibody was raised against synthetic peptide from 3rd cytoplasmic domain of human CHRM3.
- Top Product
- Discover our top product CHRM3 Primary Antibody
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- Application Notes
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Immunohistochemistry on Paraffin Sections: 5 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- Target
- CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))
- Alternative Name
- Muscarinic Acetylcholine Receptor M3 (CHRM3 Products)
- Synonyms
- EGBRS antibody, HM3 antibody, MACHR antibody, Chrm-3 antibody, M3 antibody, M3R antibody, cholinergic receptor muscarinic 3 antibody, cholinergic receptor, muscarinic 3 antibody, cholinergic receptor, muscarinic 3, cardiac antibody, CHRM3 antibody, Chrm3 antibody
- Background
- Muscarinic acetylcholine receptor 3 is an Acetylcholine Receptor that controls smooth muscle contraction by mediating phosphoinositide hydrolysis and Ca2+ mobilization. Activation of this receptor causes secretion in glandular tissues. Mouse studies suggest that the M3 receptor may play a role in appetite stimulation and food intake.Synonyms: CHRM3
- Gene ID
- 1131
- NCBI Accession
- NP_000731
- UniProt
- P20309
- Pathways
- Synaptic Membrane
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