TRPV2 antibody (N-Term)

Catalog No. ABIN302577

The Rabbit Polyclonal anti-TRPV2 antibody (ABIN302577) specifically detects TRPV2 in IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for TRPV2 antibody (N-Term) (ABIN302577)

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPV2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRPV2 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (Trpv2) at N-terminal. (Family: Ion channel, Subfamily: Calcium channel - TRP).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: TRPV2 antibody was raised against synthetic peptide from N-terminal domain of human TRPV2. Genename: TRPV2

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections (10 μg/mL). Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.8 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer.

Target Details for TRPV2

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Alternative Name: TRPV2 / VRL1

Background: Transient receptor potential vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.Synonyms: OTRPC2, Osm-9-like TRP channel 2, Transient receptor potential cation channel subfamily V member 2, VRL, VRL-1, Vanilloid receptor-like protein 1

Gene ID: 51393

NCBI Accession: NP_057197

UniProt: Q9Y5S1

Pathways: Regulation of Cell Size